Engineered Microphysiological Systems for Testing Effectiveness of Cell-Based Cancer Immunotherapies

Cell therapies, including adoptive immune cell therapies and genetically engineered chimeric antigen receptor (CAR) T or NK cells, have shown promise in treating hematologic malignancies. Yet, immune cell infiltration and expansion has proven challenging in solid tumors due to immune cell exclusion...

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Bibliographic Details
Main Authors: Campisi, Marco, Shelton, Sarah E., Chen, Minyue, Kamm, Roger D., Barbie, David A., Knelson, Erik H.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2022
Online Access:https://hdl.handle.net/1721.1/144036