Investigation of microbial responses to transition metal sequestration by the innate immune protein calprotectin
In response to microbial infection, the human host deploys metal-sequestering host-defense proteins to limit nutrient availability and thereby inhibit microbial growth and virulence. Calprotectin (CP) is an abundant antimicrobial protein that is released from neutrophils and epithelial cells at site...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/144098 |