Mechanisms of DNA damage‐mediated neurotoxicity in neurodegenerative disease
Neurons are highly susceptible to DNA damage accumulation due to their large energy requirements, elevated transcriptional activity, and long lifespan. While newer research has shown that DNA breaks and mutations may facilitate neuron diversity during development and neuronal function throughout lif...
Main Authors: | Welch, Gwyneth, Tsai, Li‐Huei |
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Other Authors: | Picower Institute for Learning and Memory |
Format: | Article |
Language: | English |
Published: |
EMBO
2022
|
Online Access: | https://hdl.handle.net/1721.1/144149 |
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