Tertiary motifs as building blocks for the design of protein‐binding peptides

Despite advances in protein engineering, the de novo design of small proteins or peptides that bind to a desired target remains a difficult task. Most computational methods search for binder structures in a library of candidate scaffolds, which can lead to designs with poor target complementarity an...

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Bibliografische gegevens
Hoofdauteurs: Swanson, Sebastian, Sivaraman, Venkatesh, Grigoryan, Gevorg, Keating, Amy E
Andere auteurs: Massachusetts Institute of Technology. Department of Biology
Formaat: Artikel
Taal:English
Gepubliceerd in: Wiley 2022
Online toegang:https://hdl.handle.net/1721.1/144152