Gene-regulatory circuitry of disease risk and progression

Complex diseases act heterogeneously through a remarkable diversity of cellular and functional outcomes across the human body, primarily through epigenetic organization and gene regulation. Genetics is a powerful tool to shed light on genes involved in disease, but we need maps of gene regulation an...

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Bibliographic Details
Main Author: Boix, Carles
Other Authors: Kellis, Manolis
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/144638