Defining the molecular basis for the β-catenin and CDC73 interaction
RNA polymerase II (Pol II) is required for expression of protein coding genes. To initiate gene transcription, Pol II is recruited to gene promoters by transcription factors. Gene specific transcription factors, including β-catenin, a component of the Wnt signaling pathway, are used to regulate gene...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/144639 |