Nutrient sensing by the mTORC1 pathway in physiology
Cellular growth and metabolism must be linked to the environmental status of the cell to maintain organismal function. This coordination is achieved by mTORC1, a master growth regulator that senses and integrates a diverse array of environmental inputs, including nutrients like glucose and the amino...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/144727 https://orcid.org/ 0000-0002-6218-0399 |