The C-Propeptide in Collagen Proteostasis
Collagen folding is initiated at the C-terminal propeptide (C-Pro) domain, a globular domain wholly distinct from the collagen’s characteristic triple helix. The C-Pro domain is responsible for assembling three collagen strands into the correct orientation and stoichiometry and nucleating folding of...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/144838 |