Transcriptional regulators in stem cell biology

Adult stem cells support tissue regeneration by both self-renewing and differentiating into specialized cell types. Analogous self-renewal and differentiation processes enable cancer stem cells to promote tumorigenesis. Transcriptional modulation, enacted by proteins including epigenetic regulators...

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Bibliographic Details
Main Author: Wilson, Molly M.
Other Authors: Lees, Jacqueline A.
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/144889