Transcriptional regulators in stem cell biology
Adult stem cells support tissue regeneration by both self-renewing and differentiating into specialized cell types. Analogous self-renewal and differentiation processes enable cancer stem cells to promote tumorigenesis. Transcriptional modulation, enacted by proteins including epigenetic regulators...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/144889 |