Development of Copper(I) Hydride-Catalyzed Asymmetric Olefin Hydrofunctionalization Reactions

The work described in this dissertation focuses on developing copper(I) hydride (CuH)-catalyzed enantioselective hydrofunctionalization reactions of olefins. The first chapter highlights a method on CuH-catalyzed asymmetric hydroamination of strained trisubstituted alkenes, including cyclobutenes an...

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Bibliographic Details
Main Author: Feng, Sheng
Other Authors: Buchwald, Stephen L.
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/144930