CellMincer: Self-Supervised Denoising of Functional Imaging
All-optical electrophysiology offers accessibility and scalability in observing neuronal activity beyond what can feasibly be achieved with patch clamp techniques. However, imaging platforms like Optopatch suffer from excessive detection noise, photobleaching, and an inability to organically segment...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/145032 |