Continuous Directed Evolution in Mammalian Cells
Directed evolution is a powerful methodology for the creation of new biomolecules with user-desired functions. Most directed evolution experiments are performed in vitro, in bacteria, or in yeast, even when the evolved biomolecule is intended to function in mammalian cells. As a result, the function...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/145089 |