Functional and Pathological States of the Protein Tau Investigated with Solid-State NMR
The microtubule-associated protein tau is expressed at high levels in human brain, and its binding and stabilization of microtubules is thought to play key roles in the maintenance of neurons. However, tau is found to pathologically aggregate into specific fibrillar structures in a number of neurode...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Published: |
Massachusetts Institute of Technology
2022
|
Online Access: | https://hdl.handle.net/1721.1/145173 https://orcid.org/ 0000-0003-3422-4734 |