Leveraging HSF1 chemical-genetic tools to elucidate mechanisms of proteostasis
Maintenance of protein function depends on an extensive network of chaperones, quality control factors, and trafficking mechanisms collectively termed the proteostasis network. This network assists folding and maintains optimal protein localization and concentration. While the components and organiz...
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Thesis |
| 出版: |
Massachusetts Institute of Technology
2022
|
| 在线阅读: | https://hdl.handle.net/1721.1/145175 https://orcid.org/0000-0001-5824-6431 |