Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial control in cynomolgus macaque lung granulomas by co...

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Bibliographic Details
Main Authors: Shalek, Alex, Love, John, Berger, Bonnie
Other Authors: Koch Institute for Integrative Cancer Research at MIT. Laboratory for Multiscale Regenerative Technologies
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/145609