Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
Mycobacterium tuberculosis lung infection results in a complex multicellular structure: the granuloma. In some granulomas, immune activity promotes bacterial clearance, but in others, bacteria persist and grow. We identified correlates of bacterial control in cynomolgus macaque lung granulomas by co...
Main Authors: | Shalek, Alex, Love, John, Berger, Bonnie |
---|---|
Other Authors: | Koch Institute for Integrative Cancer Research at MIT. Laboratory for Multiscale Regenerative Technologies |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
|
Online Access: | https://hdl.handle.net/1721.1/145609 |
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