Enantioselective Hydrocarbamoylation of Alkenes

The asymmetric hydroaminocarbonylation of olefins represents a straightforward approach for the synthesis of enantioenriched amides, but is hampered by the necessity to employ CO gas, often at elevated pressures. We herein describe, as an alternative, an enantioselective hydrocarbamoylation of alken...

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Bibliographic Details
Main Authors: Feng, Sheng, Dong, Yuyang, Buchwald, Stephen L
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Wiley 2022
Online Access:https://hdl.handle.net/1721.1/145709