CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage

Although DNA repair is known to impact susceptibility to cancer and other diseases, relatively few population studies have been performed to evaluate DNA repair kinetics in people due to the difficulty of assessing DNA repair in a high-throughput manner. Here we use the CometChip, a high-throughput...

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Bibliographic Details
Main Authors: Ngo, Le P, Kaushal, Simran, Chaim, Isaac A, Mazzucato, Patrizia, Ricciardi, Catherine, Samson, Leona D, Nagel, Zachary D, Engelward, Bevin P
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/145846