CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage
Although DNA repair is known to impact susceptibility to cancer and other diseases, relatively few population studies have been performed to evaluate DNA repair kinetics in people due to the difficulty of assessing DNA repair in a high-throughput manner. Here we use the CometChip, a high-throughput...
Main Authors: | Ngo, Le P, Kaushal, Simran, Chaim, Isaac A, Mazzucato, Patrizia, Ricciardi, Catherine, Samson, Leona D, Nagel, Zachary D, Engelward, Bevin P |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
|
Online Access: | https://hdl.handle.net/1721.1/145846 |
Similar Items
-
Applications of CometChip for Environmental Health Studies
by: Chao, Christy, et al.
Published: (2021) -
Applications of CometChip for Environmental Health Studies
by: Chao, Christy, et al.
Published: (2021) -
CometChip enables parallel analysis of multiple DNA repair activities
by: Ge, Jing, et al.
Published: (2021) -
Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates
by: Ngo, Le P, et al.
Published: (2020) -
High-Throughput Screening Platform for Engineered Nanoparticle-Mediated Genotoxicity Using CometChip Technology
by: Watson, Christa, et al.
Published: (2015)