Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts

<jats:p> This work represents the first systematic analysis of kinetochore assembly in human mitotic cell extracts. Using recombinant and native proteins, we show that only a few assembly steps are permitted, suggesting that multiple mechanisms guard against the spurious formation of microtubu...

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Bibliographic Details
Main Authors: Tarasovetc, Ekaterina V, Allu, Praveen Kumar, Wimbish, Robert T, DeLuca, Jennifer G, Cheeseman, Iain M, Black, Ben E, Grishchuk, Ekaterina L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Society for Cell Biology (ASCB) 2022
Online Access:https://hdl.handle.net/1721.1/146774