Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose

Opioid use disorder is a highly heterogeneous disease driven by a variety of genetic and environmental risk factors which have yet to be fully elucidated. Opioid overdose, the most severe outcome of opioid use disorder, remains the leading cause of accidental death in the United States. We interroga...

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Bibliographic Details
Main Authors: Corradin, Olivia, Sallari, Richard, Hoang, An T, Kassim, Bibi S, Ben Hutta, Gabriella, Cuoto, Lizette, Quach, Bryan C, Lovrenert, Katreya, Hays, Cameron, Gryder, Berkley E, Iskhakova, Marina, Cates, Hannah, Song, Yanwei, Bartels, Cynthia F, Hancock, Dana B, Mash, Deborah C, Johnson, Eric O, Akbarian, Schahram, Scacheri, Peter C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/146782