Ribonucleotide reductase, a novel drug target for gonorrhea

<jats:p>Antibiotic-resistant <jats:italic>Neisseria gonorrhoeae (Ng</jats:italic>) are an emerging public health threat due to increasing numbers of multidrug resistant (MDR) organisms. We identified two novel orally active inhibitors, PTC-847 and PTC-672, that exhibit a narrow spe...

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Bibliographic Details
Main Authors: Narasimhan, Jana, Letinski, Suzanne, Jung, Stephen P, Gerasyuto, Aleksey, Wang, Jiashi, Arnold, Michael, Chen, Guangming, Hedrick, Jean, Dumble, Melissa, Ravichandran, Kanchana, Levitz, Talya, Cui, Chang, Drennan, Catherine L, Stubbe, JoAnne, Karp, Gary, Branstrom, Arthur
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2022
Online Access:https://hdl.handle.net/1721.1/146786