Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase

Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase

© The class Ia ribonucleotide reductase of Escherichia coli requires strict regulation of long-range radical transfer between two subunits, α and β, through a series of redox-active amino acids (Y122•[β] ↔ W48?[β] ↔ Y356[β] ↔ Y731[α] ↔ Y730[α] ↔ C439[α]). Nowhere is this more precarious than at the...

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Bibliographic Details
Main Authors: Cui, Chang, Greene, Brandon L, Kang, Gyunghoon, Drennan, Catherine L, Stubbe, JoAnne, Nocera, Daniel G
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/146788

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https://hdl.handle.net/1721.1/146788

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