Multiple mechanisms for overcoming lethal over‐initiation of DNA replication

Multiple mechanisms for overcoming lethal over‐initiation of DNA replication

DNA replication is highly regulated and primarily controlled at the step of initiation. In bacteria, the replication initiator DnaA and the origin of replication oriC are the primary targets of regulation. Perturbations that increase or decrease replication initiation can cause a decrease in cell fi...

Full description

Bibliographic Details
Main Authors:	Anderson, Mary E, Smith, Janet L, Grossman, Alan D
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	English
Published:	Wiley 2022
Online Access:	https://hdl.handle.net/1721.1/146802

Similar Items

In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA
by: Smith, Janet L., et al.
Published: (2015)

In Vitro Whole Genome DNA Binding Analysis of the Bacterial Replication Initiator and Transcription Factor DnaA.
by: Janet L Smith, et al.
Published: (2015-05-01)

Genetic networks controlled by the bacterial replication initiator and transcription factor DnaA in Bacillus subtilis
by: Washington, Tracy A., et al.
Published: (2020)

Genetic and biochemical interactions between the bacterial replication initiator DnaA and the nucleoid-associated protein Rok in
by: Seid, Charlotte Allen, et al.
Published: (2018)

Regulation of DNA replication and the replication initiator, DnaA, in Bacillus subtilis
by: Anderson, Mary E.,Ph. D.(Mary Elizabeth)Massachusetts Institute of Technology.
Published: (2019)

Dynamic association of the replication initiator and transcription factor DnaA with the Bacillus subtilis chromosome during replication stress
by: Breier, Adam M., et al.
Published: (2010)

The primosomal protein DnaD inhibits cooperative DNA binding by the replication initiator DnaA in Bacillus subtilis
by: Bonilla, Carla Y., et al.
Published: (2012)

Intragenic and Extragenic Suppressors of Temperature Sensitive Mutations in the Replication Initiation Genes dnaD and dnaB of Bacillus subtilis
by: Rokop, Megan E., et al.
Published: (2010)

Intragenic and extragenic suppressors of temperature sensitive mutations replication initiation genes dnaD and dnaB of Bacillus subtilis
by: Rokop, Megan E., et al.
Published: (2010)

Intragenic and extragenic suppressors of temperature sensitive mutations in the replication initiation genes dnaD and dnaB of Bacillus subtilis.
by: Megan E Rokop, et al.
Published: (2009-08-01)

YabA of Bacillus subtilis controls DnaA-mediated replication initiation but not the transcriptional response to replication stress
by: Goranov, Alexi I., et al.
Published: (2010)

Beneficial and detrimental genes in the cellular response to replication arrest.
by: Luciane Schons-Fonseca, et al.
Published: (2022-12-01)

Beneficial and detrimental genes in the cellular response to replication arrest
by: Schons-Fonseca, Luciane, et al.
Published: (2023)

In Vivo DNA Re-replication Elicits Lethal Tissue Dysplasias
by: Sergio Muñoz, et al.
Published: (2017-05-01)

Multiple regulatory mechanisms to inhibit untimely initiation of DNA replication are important for stable genome maintenance.
by: Seiji Tanaka, et al.
Published: (2011-06-01)

Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication
by: Roberto Bellelli, et al.
Published: (2020-05-01)

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation
by: Xiaohua Xu, et al.
Published: (2023-03-01)

Movement of Replicating DNA through a Stationary Replisome
by: Lemon, Katherine P., et al.
Published: (2014)

Control of DNA Replication Initiation by Ubiquitin
by: Esperanza Hernández-Carralero, et al.
Published: (2018-09-01)

Initiation of DNA Replication: The Genomic Context.
Published: (2004-06-01)

Rapid turnover of DnaA at replication origin regions contributes to initiation control of DNA replication.
by: Katrin Schenk, et al.
Published: (2017-02-01)

Replication Initiation Proteins Regulate a Developmental Checkpoint in Bacillus subtilis
by: Kurtser, Iren, et al.
Published: (2014)

Toward an understanding of the DNA replication initiation in bacteria
by: Katarzyna Wegrzyn, et al.
Published: (2024-01-01)

Developmental regulation of DNA replication initiation in Drosophila
by: Xie, Fang, Ph. D. Massachusetts Institute of Technology
Published: (2008)

Dpb11 may function with RPA and DNA to initiate DNA replication.
by: Irina Bruck, et al.
Published: (2017-01-01)

Silencing of human DNA polymerase λ causes replication stress and is synthetically lethal with an impaired S phase checkpoint.
by: Zucca, E, et al.
Published: (2013)

Nutritional Control of Elongation of DNA Replication by (p)ppGpp
by: Wang, Jue D., et al.
Published: (2014)

ATR/Mec1 prevents lethal meiotic recombination initiation on partially replicated chromosomes in budding yeast
by: Hannah G Blitzblau, et al.
Published: (2013-10-01)

Synthetic lethality of cohesins with PARPs and replication fork mediators.
by: Jessica L McLellan, et al.
Published: (2012-01-01)

When simple sequence comparison fails: the cryptic case of the shared domains of the bacterial replication initiation proteins DnaB and DnaD
by: Marston, Farhat Y., et al.
Published: (2012)

Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response
by: Karla E. Lopez, et al.
Published: (2022-06-01)

Plasticity of DNA replication initiation in Epstein-Barr virus episomes.
by: Paolo Norio, et al.
Published: (2004-06-01)

Mechanical properties of DNA replication
by: Stuart A. Sevier
Published: (2020-06-01)

Uniform Widespread Nuclear Phosphorylation of Histone H2AX Is an Indicator of Lethal DNA Replication Stress
by: Eric Moeglin, et al.
Published: (2019-03-01)

Investigating the role of Rts1 in DNA replication initiation
by: Wallis, A, et al.
Published: (2018)

The role of CDK in the initiation step of DNA replication in eukaryotes
by: Tak Yon-Soo, et al.
Published: (2007-06-01)

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells
by: Ya Zhang, et al.
Published: (2016-06-01)

Nucleosomes influence multiple steps during replication initiation
by: Watanabe, Shinya, et al.
Published: (2017)

Nucleosomes influence multiple steps during replication initiation
by: Ishara F Azmi, et al.
Published: (2017-03-01)

Multiple regulatory systems coordinate DNA replication with cell growth in Bacillus subtilis.
by: Heath Murray, et al.
Published: (2014-10-01)