Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution

Tumor evolution is driven by the progressive acquisition of genetic and epigenetic alterations that enable uncontrolled growth and expansion to neighboring and distal tissues. The study of phylogenetic relationships between cancer cells provides key insights into these processes. Here, we introduced...

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Bibliographic Details
Main Authors: Yang, Dian, Jones, Matthew G, Naranjo, Santiago, Rideout, William M, Min, Kyung Hoi Joseph, Ho, Raymond, Wu, Wei, Replogle, Joseph M, Page, Jennifer L, Quinn, Jeffrey J, Horns, Felix, Qiu, Xiaojie, Chen, Michael Z, Freed-Pastor, William A, McGinnis, Christopher S, Patterson, David M, Gartner, Zev J, Chow, Eric D, Bivona, Trever G, Chan, Michelle M, Yosef, Nir, Jacks, Tyler, Weissman, Jonathan S
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/146823