Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
Tumor evolution is driven by the progressive acquisition of genetic and epigenetic alterations that enable uncontrolled growth and expansion to neighboring and distal tissues. The study of phylogenetic relationships between cancer cells provides key insights into these processes. Here, we introduced...
Main Authors: | Yang, Dian, Jones, Matthew G, Naranjo, Santiago, Rideout, William M, Min, Kyung Hoi Joseph, Ho, Raymond, Wu, Wei, Replogle, Joseph M, Page, Jennifer L, Quinn, Jeffrey J, Horns, Felix, Qiu, Xiaojie, Chen, Michael Z, Freed-Pastor, William A, McGinnis, Christopher S, Patterson, David M, Gartner, Zev J, Chow, Eric D, Bivona, Trever G, Chan, Michelle M, Yosef, Nir, Jacks, Tyler, Weissman, Jonathan S |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
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Online Access: | https://hdl.handle.net/1721.1/146823 |
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