Development of a physiological insulin resistance model in human stem cell–derived adipocytes

<jats:p>Adipocytes are key regulators of human metabolism, and their dysfunction in insulin signaling is central to metabolic diseases including type II diabetes mellitus (T2D). However, the progression of insulin resistance into T2D is still poorly understood. This limited understanding is du...

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Bibliographic Details
Main Authors: Friesen, Max, Khalil, Andrew S, Barrasa, M Inmaculada, Jeppesen, Jacob F, Mooney, David J, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022
Online Access:https://hdl.handle.net/1721.1/146840