Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease

<jats:p>For Alzheimer’s disease–a leading cause of dementia and global morbidity–improved identification of presymptomatic high-risk individuals and identification of new circulating biomarkers are key public health needs. Here, we tested the hypothesis that a polygenic predictor of risk for A...

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Bibliographic Details
Main Authors: Paranjpe, Manish D, Chaffin, Mark, Zahid, Sohail, Ritchie, Scott, Rotter, Jerome I, Rich, Stephen S, Gerszten, Robert, Guo, Xiuqing, Heckbert, Susan, Tracy, Russ, Danesh, John, Lander, Eric S, Inouye, Michael, Kathiresan, Sekar, Butterworth, Adam S, Khera, Amit V
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022
Online Access:https://hdl.handle.net/1721.1/146853