Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

<jats:p>Gene duplication is crucial to generating novel signaling pathways during evolution. However, it remains unclear how the redundant proteins produced by gene duplication ultimately acquire new interaction specificities to establish insulated paralogous signaling pathways. Here, we used...

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Bibliographic Details
Main Authors: Nocedal, Isabel, Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2022
Online Access:https://hdl.handle.net/1721.1/146866