Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity
<jats:p>Gene duplication is crucial to generating novel signaling pathways during evolution. However, it remains unclear how the redundant proteins produced by gene duplication ultimately acquire new interaction specificities to establish insulated paralogous signaling pathways. Here, we used...
Main Authors: | Nocedal, Isabel, Laub, Michael T |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2022
|
Online Access: | https://hdl.handle.net/1721.1/146866 |
Similar Items
-
Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity
by: Isabel Nocedal, et al.
Published: (2022-06-01) -
Ancestral reconstruction reveals mechanisms of ERK regulatory evolution
by: Dajun Sang, et al.
Published: (2019-08-01) -
Sucrose-phosphate phosphatase from sugarcane reveals an ancestral tandem duplication
by: Vania Gabriela Sedano Partida, et al.
Published: (2021-01-01) -
Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library
by: Lite, Thuy-Lan V, et al.
Published: (2021) -
Uncovering the basis of protein-protein interaction specificity with a combinatorially complete library
by: Thuy-Lan V Lite, et al.
Published: (2020-10-01)