The evolution of a counter-defense mechanism in a virus constrains its host range

<jats:p>Bacteria use diverse immunity mechanisms to defend themselves against their viral predators, bacteriophages. In turn, phages can acquire counter-defense systems, but it remains unclear how such mechanisms arise and what factors constrain viral evolution. Here, we experimentally evolved...

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Bibliographic Details
Main Authors: Srikant, Sriram, Guegler, Chantal K, Laub, Michael T
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd 2022
Online Access:https://hdl.handle.net/1721.1/146868