E2F4’s cytoplasmic role in multiciliogenesis is mediated via an N-terminal domain that binds two components of the centriole replication machinery, Deup1 and SAS6
<jats:p> Multiciliogenesis requires both nuclear and cytoplasmic functions of the E2F4 transcription factor. Here we identify a domain in E2F4 that interacts with two key components of the cytoplasmic centriole replication machinery, Deup1 and SAS6, and is sufficient to mediate E2F4’s cytoplas...
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Bibliographic Details
| Main Authors: |
Hazan, Renin,
Mori, Munemasa,
Danielian, Paul S,
Guen, Vincent J,
Rubin, Seth M,
Cardoso, Wellington V,
Lees, Jacqueline A |
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| Other Authors: |
Massachusetts Institute of Technology. Department of Biology |
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| Format: | Article
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| Language: | English |
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| Published: |
American Society for Cell Biology (ASCB)
2022
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| Online Access: | https://hdl.handle.net/1721.1/146881
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