A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth
<jats:p>Long noncoding RNAs (lncRNA) can drive tumorigenesis and are susceptible to therapeutic intervention. Here, we used a large-scale CRISPR interference viability screen to interrogate cell growth dependency to lncRNA genes in multiple myeloma (MM), and identified a prominent role for the...
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| Format: | Article |
| Language: | English |
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American Society of Hematology
2023
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| Online Access: | https://hdl.handle.net/1721.1/147017 |