Nucleotide imbalance decouples cell growth from cell proliferation

<jats:title>Abstract</jats:title><jats:p>Nucleotide metabolism supports RNA synthesis and DNA replication to enable cell growth and division. Nucleotide depletion can inhibit cell growth and proliferation, but how cells sense and respond to changes in the relative levels of individ...

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Bibliographic Details
Main Authors: Diehl, Frances F, Miettinen, Teemu P, Elbashir, Ryan, Nabel, Christopher S, Darnell, Alicia M, Do, Brian T, Manalis, Scott R, Lewis, Caroline A, Vander Heiden, Matthew G
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147019