Design and synthesis of a new orthogonally protected glutamic acid analog and its use in the preparation of high affinity polo-like kinase 1 polo-box domain – binding peptide macrocycles
<jats:p>A novel macrocyclic peptide strategy utilizing a glutamic acid analog that can work as an alkylated histidine replacement.</jats:p>
Bibliographic Details
| Main Authors: |
Hymel, David,
Tsuji, Kohei,
Grant, Robert A,
Chingle, Ramesh M,
Kunciw, Dominique L,
Yaffe, Michael B,
Burke, Terrence R |
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| Other Authors: |
Massachusetts Institute of Technology. Department of Biology |
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| Format: | Article
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| Language: | English |
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| Published: |
Royal Society of Chemistry (RSC)
2023
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| Online Access: | https://hdl.handle.net/1721.1/147021
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