Compatibility rules of human enhancer and promoter sequences

Gene regulation in the human genome is controlled by distal enhancers that activate specific nearby promoters1. A proposed model for this specificity is that promoters have sequence-encoded preferences for certain enhancers, for example, mediated by interacting sets of transcription factors or cofac...

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Bibliographic Details
Main Authors: Bergman, Drew T, Jones, Thouis R, Liu, Vincent, Ray, Judhajeet, Jagoda, Evelyn, Siraj, Layla, Kang, Helen Y, Nasser, Joseph, Kane, Michael, Rios, Antonio, Nguyen, Tung H, Grossman, Sharon R, Fulco, Charles P, Lander, Eric S, Engreitz, Jesse M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147044