Thermal Proteome Profiling to Identify Protein-ligand Interactions in the Apicomplexan Parasite Toxoplasma gondii

Toxoplasma gondii is a single-celled eukaryotic parasite that chronically infects a quarter of the global population. In recent years, phenotypic screens have identified compounds that block parasite replication. Unraveling the pathways and molecular mechanisms perturbed by such compounds requires t...

Full description

Bibliographic Details
Main Authors: Herneisen, Alice, Lourido, Sebastian
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Bio-Protocol, LLC 2023
Online Access:https://hdl.handle.net/1721.1/147078