Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular heterogeneity, and immunogenic potential may reveal diagnostic and therapeutic insights when analyzed at high resolution. We present a single-cell transcriptomic and imaging atlas of the two most common human col...
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Format: | Article |
Language: | English |
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Elsevier BV
2023
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Online Access: | https://hdl.handle.net/1721.1/147095 |