Integrated, single-cell analysis of transcriptional phenotype and clonotypic identity
Single-cell RNA sequencing (scRNA-seq) currently affords the ability to resolve whole transcriptomes of single cells with substantial throughput and has revolutionized studies of gene expression. Recent technical advances have enabled the matching of T cell receptor (TCR) and B cell receptor (BCR) v...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/147228 |