Transcriptome-wide pseudouridine profiling reveals modification of critical E. coli mRNAs

Pseudouridine (Ψ) is an ubiquitous RNA modification, present in the tRNAs and rRNAs of species across all domains of life, and is now known to be present in the mRNAs of diverse eukaryotes. However, the modification was yet to be identified in bacterial mRNAs, and its functional roles remain largely...

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Bibliographic Details
Main Author: Schaening Burgos, Cassandra
Other Authors: Gilbert, Wendy V.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/147253