The Roles of the Mcm2-7 Tails in Replication Initiation
DNA replication is complex biological reaction that spans two stages of the eukaryotic cell cycle. In G1 phase, preparation for replication begins when two copies of the replicative helicase, the Mcm2-7 complex, are loaded onto DNA. However, these helicases are loaded in an inactive state, and are n...
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Format: | Thesis |
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Massachusetts Institute of Technology
2023
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Online Access: | https://hdl.handle.net/1721.1/147266 https://orcid.org/0000-0002-4893-8167 |