Single-cell differential splicing of Alzheimer’s Disease in 1.9 million cells across 416 individuals
Alzheimer’s Disease (AD) is a polygenic disease with variable phenotypic response among patients. While single-cell differential expression data can provide important information regarding the disease’s pathology, it only captures steady-state cell behavior. By contrast, RNA velocity analysis allows...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Published: |
Massachusetts Institute of Technology
2023
|
| Online Access: | https://hdl.handle.net/1721.1/147438 |