Dynast: Inclusive and efficient quantification of metabolically labeled transcripts in single cells
Single cell RNA velocity, defined as the time derivative of gene expression, is a powerful concept that can predict the future transcriptional state of the cell. Traditionally, RNA velocity estimations relied on the distinction between spliced and unspliced mRNA in single cell RNA-seq (scRNA-seq) da...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2023
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| Online Access: | https://hdl.handle.net/1721.1/147475 |