Communication & coordination between components of the ClpAP degradation machine

AAA+ (ATPases associated with diverse cellular activities) proteases are present in all kingdoms of life. These molecular machines perform energy-dependent regulated proteolysis. The bacterial enzyme ClpA is a double-ring hexameric AAA+ unfoldase/translocase that functions with the tetradecameric Cl...

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Bibliographic Details
Main Author: Zuromski, Kristin L.
Other Authors: Baker, Tania A.
Format: Thesis
Published: Massachusetts Institute of Technology 2023
Online Access:https://hdl.handle.net/1721.1/147731
https://orcid.org/0000-0003-0960-5009