Communication & coordination between components of the ClpAP degradation machine
AAA+ (ATPases associated with diverse cellular activities) proteases are present in all kingdoms of life. These molecular machines perform energy-dependent regulated proteolysis. The bacterial enzyme ClpA is a double-ring hexameric AAA+ unfoldase/translocase that functions with the tetradecameric Cl...
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| 格式: | Thesis |
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Massachusetts Institute of Technology
2023
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| 在线阅读: | https://hdl.handle.net/1721.1/147731 https://orcid.org/0000-0003-0960-5009 |