Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders

Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders

Viruslike particles (VLPs) fabricated using wireframe DNA origami are emerging as promising vaccine and gene therapeutic delivery platforms due to their programmable nature that offers independent control over their size and shape, as well as their site-specific functionalization. As materials that...

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Bibliographic Details
Main Authors: Wamhoff, Eike-Christian, Romanov, Anna, Huang, Hellen, Read, Benjamin J, Ginsburg, Eric, Knappe, Grant A, Kim, Hyun Min, Farrell, Nicholas P, Irvine, Darrell J, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Chemical Society (ACS) 2023
Online Access:https://hdl.handle.net/1721.1/147761

Internet

https://hdl.handle.net/1721.1/147761

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