Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders
Viruslike particles (VLPs) fabricated using wireframe DNA origami are emerging as promising vaccine and gene therapeutic delivery platforms due to their programmable nature that offers independent control over their size and shape, as well as their site-specific functionalization. As materials that...
Main Authors: | Wamhoff, Eike-Christian, Romanov, Anna, Huang, Hellen, Read, Benjamin J, Ginsburg, Eric, Knappe, Grant A, Kim, Hyun Min, Farrell, Nicholas P, Irvine, Darrell J, Bathe, Mark |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2023
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Online Access: | https://hdl.handle.net/1721.1/147761 |
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