Innate Immune Stimulation Using 3D Wireframe DNA Origami

Three-dimensional wireframe DNA origami have programmable structural and sequence features that render them potentially suitable for prophylactic and therapeutic applications. However, their innate immunological properties, which stem from parameters including geometric shape and cytosine-phosphate-...

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Bibliographic Details
Main Authors: Du, Rebecca R, Cedrone, Edward, Romanov, Anna, Falkovich, Reuven, Dobrovolskaia, Marina A, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Chemical Society (ACS) 2023
Online Access:https://hdl.handle.net/1721.1/147762