Pooled genetic perturbation screens with image-based phenotypes

Discovery of the genetic components underpinning fundamental and disease-related processes is being rapidly accelerated by combining efficient, programmable genetic engineering with phenotypic readouts of high spatial, temporal and/or molecular resolution. Microscopy is a fundamental tool for studyi...

Full description

Bibliographic Details
Main Authors: Feldman, David, Funk, Luke, Le, Anna, Carlson, Rebecca J, Leiken, Michael D, Tsai, FuNien, Soong, Brian, Singh, Avtar, Blainey, Paul C
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147776