Pooled genetic perturbation screens with image-based phenotypes
Discovery of the genetic components underpinning fundamental and disease-related processes is being rapidly accelerated by combining efficient, programmable genetic engineering with phenotypic readouts of high spatial, temporal and/or molecular resolution. Microscopy is a fundamental tool for studyi...
Main Authors: | Feldman, David, Funk, Luke, Le, Anna, Carlson, Rebecca J, Leiken, Michael D, Tsai, FuNien, Soong, Brian, Singh, Avtar, Blainey, Paul C |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2023
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Online Access: | https://hdl.handle.net/1721.1/147776 |
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