The cellular architecture of the antimicrobial response network in human leprosy granulomas

The cellular architecture of the antimicrobial response network in human leprosy granulomas

Granulomas are complex cellular structures composed predominantly of macrophages and lymphocytes that function to contain and kill invading pathogens. Here, we investigated the single-cell phenotypes associated with antimicrobial responses in human leprosy granulomas by applying single-cell and spat...

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Bibliographic Details
Main Authors: Ma, Feiyang, Hughes, Travis K, Teles, Rosane MB, Andrade, Priscila R, de Andrade Silva, Bruno J, Plazyo, Olesya, Tsoi, Lam C, Do, Tran, Wadsworth, Marc H, Oulee, Aislyn, Ochoa, Maria Teresa, Sarno, Euzenir N, Iruela-Arispe, M Luisa, Klechevsky, Eynav, Bryson, Bryan, Shalek, Alex K, Bloom, Barry R, Gudjonsson, Johann E, Pellegrini, Matteo, Modlin, Robert L
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2023
Online Access:https://hdl.handle.net/1721.1/147779

Internet

https://hdl.handle.net/1721.1/147779

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